*
Radiological Chemistry
*
About Us   Faculty   Major Grants   Interests   Jobs   Contact
*
*
* *


 
Cyclotron Produced Isotopes in Biology and Medicine - Publication List
| Articles | Abstracts |
 
Articles
[ Return to top ]
  • Hostetler ED, Fallis S, McCarthy TJ, Welch MJ and Katzenellenbogen JA. Improved methods for the synthesis of [ω-11C]palmitic acid. J. Org. Chem. 63:1348-1351, 1998.
  • Kazushige O, Bernstein ML, Zhang W, Schuster DP, and Botney MD. Angiotensin-converting enzyme inhibition delays pulmonary vascular neointimal formation. Am. J. Respir. Crit. Care Med. 158:939-950, 1998.
  • Downer JB, Margenau WH, and Welch MJ. Heated nitrogen to rapidly evaporate solutions. J. Labelled Cpd. Radiopharm. 42 Suppl. 1:S900-S902, 1999.
  • Fujibayashi Y, Cutler CS, Anderson CJ, McCarthy DW, Jones LA, Sharp T, Yonekura Y and Welch MJ. Comparative studies of Cu-64-ATSM and C-11-acetate in an acute myocardial infarction model: Ex vivo imaging of hypoxia in rats. Nucl. Med. Biol. 26:117-121,1999.
  • Lewis JS, McCarthy DW, McCarthy TJ, Fujibayashi Y and Welch MJ. The evaluation of 64Cu-diacetyl-bis(N4-methylthiosemicarbazone)(64Cu-ATSM) In vitro and in vivo in a hypoxic tumor model. J. Nucl. Med. 40:177-183, 1999.
  • Hostetler ED, Edwards WB, Anderson CJ and Welch MJ. Synthesis of 4-[18F]fluorobenzoyl octreotide and biodistribution in tumor-bearing lewis rats. J. Labelled Cpd. Radiopharm. 42(Suppl. 1):S720-S721, 1999.
  • Jonson SD, Jones LA and Welch MJ. Tumor uptake of potential ligands for the peroxisome proliferator activated receptor. J. Labelled Cpd. Radiopharm. 42(Suppl.1):S710-S712, 1999.
  • Qing F, McCarthy TJ, Markham J, and Schuster DP. Pulmonary angiotensin-converting enzyme (ACE) binding and inhibition in humans: a positron emission tomography study. Am. J. Respir. Crit. Care Med.. 161:1-7, 2000.
  • Wuest F, Dence CS, McCarthy TJ, and Welch MJ. A new approach for the synthesis of [11C]-labeled fatty acids. J. Labeled Comp. Radiopharm. 43:1289-1304, 2000.
  • Chen X, Edwards WB, Anderson CJ, McCarthy TJ, and Welch MJ. Solid phase synthesis of TETA conjugated vasoactive intestinal peptide and in vivo behavior of copper-64 radiolabeled VIP conjugate. J. Labelled Cpd. Radiopharm. 44:S688-S690, 2001.
  • Dence CD, Powers WJ, and Welch MJ. A simple approach to the synthesis of [C-11]-D-mannitol and [C-11]-D-glucitol (Sorbitol). J. Labelled Cpd. Radiopharm. 44:S137-S139, 2001.
  • Gropler RJ. Impact of aging on myocardial oxidative metabolism. Heart and Metabolism 15:14-18, 2001.
  • Gust R and Schuster DP. Vascular remodeling in experimentally-induced subacute canine pulmonary hypertension. Exp. Lung. Res. 27:1-12, 2001.
  • Mintun MA, Lundstrom BN, Snyder AZ, Vlassenko AG, Shulman GL and Raichle ME. Blood flow and oxygen delivery to human brain during functional activity: Theoretical modeling and experimental data. Proc. Natl. Acad. Sci. USA 58:6859-6864, 2001.
  • Schwarz S, Margenau W, McCarthy TJ, and Welch MJ. Radiopharmaceutical scheduling center with six PET scanners. J. Labelled Comp. Radiopharm. 44(Suppl. 1):S1063-S1065, 2001.
  • Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, and Kelly DP. The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus. J. Clin. Invest. 109:121-130, 2002.
  • Herrero P, Sharp T, Dence C, Haraden BA and Gropler RJ. Comparison of 1-11C-glucose with 18F-fluorodeoxyglucose for quantifying myocardial glucose utilization with positron emission tomography. J. Nucl. Med. 43:1530-1541, 2002.
  • Herrero P, Weinheimer C, Dence C, Oellerich WF, and Gropler RJ. Quantification of myocardial glucose utilization by PET and 1-11C-glucose. J. Nucl. Cardiol. 9:5-14, 2002.
  • Jonson SD and Welch MJ. Investigations into tumor accumulation and peroxisome proliferator activated receptor binding by F-18 and C-11 fatty acids. Nucl. Med. Biol. 29:211-216, 2002.
  • McCarthy TJ, Sheriff AU, Graneto MJ, Talley JJ, and Welch MJ. Radiosynthesis in vitro validation and in vivo evaluation of 18F-labeled COX-1 and COX-2 inhibitors. J. Nucl. Med. 43:117-124, 2002.
  • Mintun MA, Vlassenko AG, Shulman GL. and Snyder AZ. Time-related increase of oxygen utilization in continuously activated human visual cortex. NeuroImage, 16(2):531-537, 2002.
  • Davila-Roman VG, Vedala G, Herrero P, de las Fuentes L, Rogers JG, Kelly DP, and Gropler RJ. Altered fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy. J. Am. Coll. Cardiol., 40(2):271-277, 2002.
  • Kates AM, Herrero P, Dence C, Soto P, Srinivasan M, Delano DG, Ehsani A and Gropler RJ. Impact of aging on substrate metabolism by the human heart. J. Am. Coll. Cardiol. 41(2):293-299, 2003.
  • Lewis JS, Herrero P, Sharp TL, Engelbach JA, Fujibayashi Y, Laforest R, Kovacs A, Gropler RJ, and Welch MJ. Delineation of hypoxia in canine myocardium using copper-diacetyl-bis(N4-methylthiosemicabazone) and PET. J. Nucl. Med. 43:1557-1569, 2002.
  • Schuster DP, Kozlowski J, Hogue L, and Ferkol TW. Imaging lung inflammation in a murine model of Pseudomonas infection: a positron emission tomography study. Exp. Lung Res. 29:45-57, 2003.
  • Waggoner AD, Barzalai B, Nasser A, de las Fuentes L, Rogers JA, Gropler RJ and Davila-Roman VG. Diastolic function in patients with left ventricular systolic dysfunction: assessment by tissue dopler imaging. J. Am. Soc. Echocardiography, 40(2):271-277, 2002.
  • Richard J-C, Zhou Z, Ponde DC, Dence CS, Factor P, Reynolds PN, Luker GD, Sharma V, Ferkol T, Piwnica-Worms D, Schuster DP. Imaging pulmonary gene expression with positron emission tomography (PET). Am. J. Resp. Crit. Care Med., in press.
  • Herrero P, Dence C, Sharp T, Welch MJ and Gropler RJ. Impact of reversible trapping of tracer and presence of blood metabolites on measurements of myocardial glucose utilization performed by PET and 18F fluorodeoxyglucose using the Patlak method. Submitted for publication, J. Nucl. Med.
Return to top
 
Abstracts
[ Return to top ]
  • Welch MJ, Lewis JS, McCarthy DW, Sharp T, Herrero P, and Fujibayashi Y. Evaluation of Copper-60-diacetyl-bis(N4-methylthiosemicarbazone)(Cu-ATSM), a hypoxia imaging agents, in canine models of ischemia. Eur. J. Nucl. Med. 25(8): 920P, 1988.
  • Herrero P, McCarthy DW, Lewis JS, Sharp TL, Fujibayashi Y, Gropler RJ, and Welch MJ. Evaluation of myocardial kinetics of the hypoxic imaging agent copper-60-diacetyl-bis(N4-methylthiosemicarbazone)(Cu-ATSM). Circulation 98: I-581, 1998.
  • Lewis JS, McCarthy DW, Cristel ME, and Welch MJ. In vitro and in vivo evaluation of copper-radiolabeled hypoxia targeting agents in the EMT6 hypoxic tumor model. J. Nucl. Med. 39(5):91P, 1998.
  • Herrero P, Sharp TL, Dence CS, Haraden BM, Potts NV, and Gropler RJ. How constant is the lump constant in myocardial 18F-FDG imaging during hyperinsulinemic euglycemic clamp. J. Nucl. Med. 40:824P, 1999.
  • Herrero P, Sharp TL, Dence CS, Haraden BM, Potts NV, and Gropler RJ. Accuracy of myocardial glucose utilization measurements obtained with 1-11C-glucose without correction of blood activity for metabolites. J Nucl. Med. 40:842P, 1999.
  • Herrero P, Sharp TL, Dence CS, Haraden BM, Potts NV, and Gropler RJ. Demonstration of reversible myocardial trapping of F-18 Fluorodeoxyglucose. Circulation (suppl.) 100:457, 1999.
  • Qing F, McCarthy TJ, Markham J, and Schuster DP. Dose of angiotensin-converting enzyme (ACE) inhibitor required to block lung ace, determined by positron emission tomography (PET). Am. J. Respir. Crit. Care Med. 159:A166, 1999.
  • Vedala G, Gropler RJ, Kates AM, Herrero P, and Davila-Roman VG. Decreased myocardial fatty acid utilization in patients with hypertension induced left ventricular hypertrophy. Circulation (suppl.) 100:116,1999.
  • Herrero P, Kates AM, Vedela G, Davila-Roman VG, and Gropler RJ. The myocardial metabolic response to catecholamines is dependent upon the substrate environment. Supplement to J. Am. Coll. Cardiol. 35:481A, 2000.
  • Beerepoot J, Herrero P, Vedala G, Delano DA, Ehsani E, Davila-Roman VG, and Gropler RJ. The impact of age and gender on the response of myocardial perfusion and oxygen consumption to dobutamine. Presented at the European Association of Nuclear Medicine Annual Congress Paris, France, September, 2000.
  • Hostetler E, Deal KA, McCarthy TJ, Lewis JS, and Welch MJ. Synthesis and in vitro evaluation of a new 18F labeled potential diagnostic imaging agent for hypoxic tissue. J. Nucl. Med. 41(5):115P, 2000.
  • Rogers J, Herrero P, Delano DA, Kelly DP, Davila-Roman VG. And Gropler RJ. Demonstration of a shift in myocardial intermediary metabolism in the failing human heart. Circulation (suppl.) 102:3880, 2000.
  • Sharp TL, Lewis JS, Herrero P, Engelbach JA, Fujibayashi Y, Gropler RJ, and Welch MJ. Quantification of Cu-ATSM kinetics by compartmental modeling in normal, ischemic and necrotic myocardium. J. Nucl. Med. 41(5):115P, 2000.
  • Vedala G, Herrero P, Kates AM, Potts Nv, Grochowalski DL, Davila-Roman VG, and Gropler RJ. Additive effects of aging and hypertensive left ventricular hypertrophy on myocardial fatty acid utilization in humans. J. Nucl. Med. 41:344, 2000.
  • Wuest F, Dence CS, McCarthy TJ, and Welch MJ. A new approach for the synthesis of 11C-labeled fatty acids. J. Nucl. Med. 41(5):123P, 2000.
  • Dence CS, Herrero P, Sharp TL, and Welch MJ. Analysis of acidic metabolites following injections of 1-11C-D-Glucose and 18F-FDG in patients and Dogs. Abstract, 12th International Symposium of Radiopharmacology, 2001.
  • Kim J, Herrero P, Markham J, McCarthy TJ, Welch MJ, and Schuster DP. In vivo measurements of pulmonary angiotensin-converting enzyme kinetics. J. Nucl. Med. 42(Suppl. 5):191P, 2001.
  • Chen X, Edwards WB, Anderson CJ, McCarthy TJ, and Welch MJ. Solid phase synthesis of TETA conjugate. J. Labelled Cpd. Radiopharm. 44:S688-S690, 2001.
  • Gropler RJ, Herrero P, Vedala G, Delano DA, and Ehsani E. Impact of aging on dobutamine-induced changes in myocardial intermediary metabolism. J. Nucl. Med. 42(Suppl. 5): 52P, 2001.
  • Herrero P, Beerepoot J, Vedala G, Delano DA, Ehsani E, Davil-Roman VG, and Gropler RJ. The impact of age and gender on the response to myocardial perfusion and oxygen consumption to catecholamineses. Presented at the 5th International Congress in Nuclear Cardiology, Vienna, Austria, May 2-5, 2001.
  • Herrero P, Eshani A, Delano DA, and Gropler RJ. The impact of age and gender on resting myocardial perfusion and oxygen consumption. J. Nucl. Med. 42(Suppl. 5):96P, 2001.
  • Herrero P, Kisrieva-Ware Z, Delano D, Vedala G, Ehsani A, and Gropler RJ. The impact of age and gender on myocardial perfusion and oxygen consumption. J. Nucl. Med. 42:360, 2001.
  • Herrero P, Vedala G, Kowalski R, Ehsani A, Delano D, Davila-Roman V, and Gropler RJ. Impact of aging on dobutamine-induced changes in myocardial substrate utilization. J. Nucl. Med. 42:196, 2001.
  • Sharp TL, Engelbach JA, and Welch MJ. Procedures for animal handling in microPET studies. Abstract, 12th International Symposium of Radiopharmacology, 2001.
  • Sharp TL, Gaehle G, Engelbach JA, and Welch MJ. Advances in techniques and procedures for small animal handling for microPET studies. High resolution imaging in small animals: Instrumentation, Application and Animal Handling, Rockville, Maryland, 2001.
  • Vedala G, de las Fuentes L, Nasser A, Herrero P, Gropler RJ, and Davial-Roman VG. Reduced fatty acid utilization and oxidation in hypertensive LVH with inotropic stimulation. Circulation (suppl.) 104:2367, 2001.
  • Welch MJ, Lewis JS, Herrero P, Sharp TL, Engelbach JA, and Gropler RJ. Detection of coronary artery stenosis induced ischemia with Cu-ATSM-PET. Abstract, European Association of Nuclear Medicine, 2001.
  • Kim J, Herrero P, Markham J, McCarthy TJ, and Schuster DP. In vivo measurements of pulmonary angiotensin-converting enzyme kinetics J. Nucl. Med. 42(Suppl 5): 191A, 2001.
  • Herrero P, Cassady D, Kisrieva-Ware Z, Srinivasan M, McGill J, and Gropler RJ. Myocardial fatty acid oxidation is increased in patients with insulin dependent diabetes mellitus. J. Nucl. Med. 43(5):140P, 2002.
  • Herrero P, Cassady D, Kisrieva-Ware Z, Srinivasan M, McGill J, and Gropler RJ. Myocardial fatty acid oxidation is increased in patients with insulin dependent diabetes mellitus. Congress of the European Society of Cardiology, August 2002.
  • Peterson LP, Waggoner AD, Meyer T, Gropler RJ, Perez J, Johnston D, and Davila-Roman VG. Tissue Doppler imaging detects systolic and diastolic abnormalities in young obese women. Annual Meeting of the American Society of Echocardiography, June 2002.
  • Vedala G, McGill JB, Herrero P, Cassady DS, and Gropler RJ. Impact of plasma insulin and glucose on myocardial vascular function in patients with IDDM. Circulation (suppl.) 102:2802, 2002.
  • Gropler RJ, Herrero P, Vedala G, Cassady D, and McGill JB. Early effects of hyperinsulinemia and hyperglycemia on myocardial perfusion and perfusion reserve in type 1 diabetes. 73rd Annual Scientific Sessions of the American Heart Association.
Return to top
* *